Secureframe is a compliance-automation product with a growing federal-and-defense specialization. vCISO Lite is a security & cyber-risk platform of which compliance automation is one surface. The overlap is narrower than the shared category naming suggests.
Pick Secureframe when the compliance workload is the whole workload AND the buyer needs deep federal / defense framework coverage (CMMC 2.0, FedRAMP, NIST 800-53, NIST 800-171). The 2025 launches (Secureframe Federal, Custom Integrations) and April 2026 User Access Reviews are aimed squarely at that buyer.
Pick vCISO Lite when the audit is the price of entry and the work is broader — cyber risk quantified in dollars for a board, vendor-incident exposure computed within hours of a disclosed breach, M&A cyber diligence, or education-sector coverage (CIPA, COPPA, FERPA) Secureframe does not ship. Published pricing starts at $3,228 / yr (billed annually).
Secureframe’s vendor risk module logs a live incident and continues sending questionnaires; it doesn’t re-compute the buyer’s exposure. vCISO Lite ships DC-TPIR productized as Refraction, which re-derives conditional dollar exposure hourly while the incident is live. Detail in §4.1.